Serology of infectious diseases

Serological methods of testing are aimed at highlighting specific antibodies directed against a microbial or viral aggressor. They indirectly demonstrate the presence of a current infection or a previous infection.
The detected biological signal is represented by antibodies of IgM or IgG classes specific to microbial surface antigens.
Serological tests can measure the level of protective antibodies and also detect variations in their concentration, thus demonstrating the presence of infection. For detection of antibody titer variation (quantitative assessment), measurements should be repeated every 10-14 days.
Detection of IgM antibodies in the asymptomatic phase of the disease is an early response of the body to infection. A fourfold increase in the concentration of antibodies (antibody titer) in samples collected in the acute phase of the disease is evidence of the existence of an acute infection.
The specialist doctor can prescribe serological tests to confirm the presence or absence of antibodies in some infectious pathologies.